You’ve likely seen cannabidiol (CBD) everywhere from drugstore gummies to boutique coffee concoctions. But there’s reason to believe smoking high-CBD flower might be one of the most effective ways to experience the potential benefits of CBD.

If you’re curious about smoking CBD flower and want to explore the pros and cons, this is the guide for you. And if you’re looking for a literal guide to smoking, we have a guide for that, too. 

Why this happens has to do with how THC and CBD interact with the body’s endocannabinoid system (ECS). The human endocannabinoid system consists of the cannabinoid receptors found throughout the body. The body’s most studied cannabinoid receptors are the Cannabinoid-1 and Cannabinoid-2 receptors (CB1 and CB2), and they are found in the central nervous system, the peripheral nervous system, and the immune system. 

THC binds with the CB1 receptors in the brain to produce that classic weed high, while CBD has been shown to have the opposite interaction with CB1 receptors, acting as an antagonist. When consumed together, CBD appears to improve the therapeutic and enjoyable effects of THC by minimizing the unwanted side effects such as anxiety and a rapid heartbeat.

Post credited to: Weedmaps Editors on